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PSC - Item 3E.D - Attachment D - NARCAN Quick Start GuideSIE NARCAN(nalaxone HCI) Q U I C S START Gk I NASAL SPRAY Opioid Overdose Response Instructions Use NARCAN Nasal Spray (naloxone hydrochloride) for known or suspected opioid overdose in adults and children. Important: For use in the nose only. Do not remove or test the NARCAN Nasal Spray until ready to use. Identify Opioid Overdose I and Check for Response Give NARCAN Nasal Spray Call for emergency medical help, Evaluate, and Support Ask person if he or she is okay and shout name. Shake shoulders and firmly rub the middle of their chest. At Check for signs of opioid overdose: • Will not wake up or respond to your voice or touch • Breathing is very slow, irregular, or has stopped • Center part of their eye is very small, sometimes called "pinpoint pupils" Lay the person on their back to receive a dose of NARCAN Nasal Spray. eoo.e only Rz Only ♦yOr emove NARCAN Nasal Spray from the box. ®NARCANi�M"ffll 4 NASAL SPRAY a mg Peel back the tab with the circle to open the NARCAN Nasal Spray. IIIIIIIIIII _ �'' ��Z Each dose -in 4 mg naloxone HCI in 0.1 mL nasal spray l 'prey gerund Score et room temperature between 59°Fto 77°F OFT to 25°C) Excursions permitted been SM. IOVF WC m 40°C) Oo not freeze. Protect from light. Use kr known or suspected opioid overdose 'n adults end children SEE ENCLOSED QUICK START GUIDE LOT_00000 & E%P MMM/YYY= Di -mad by -pt --I... R-or,PA19[81 USA A' gl 00 NOTTEST DEVICE BEFORE USE Viola the NARCAN nasal spray with your thumb on the bottom of the plunger and your first and middle fingers on either side of the nozzle. Gently insert the tip of the nozzle into either nostril. • Tilt the person's head back and provide support under the neck with your hand. Gently insert the tip of the nozzle into one nostril, until yourfingers on either side of the nozzle are against the bottom of the person's nose. Press the plunger firmly to give the dose of NARCAN Nasal Spray. • Remove the NARCAN Nasal Spray from the nostril after giving the dose. vet emergency medical help right away. Move the person on their side (recovery position) after giving NARCAN Nasal Spray. Watch the person closely. If the person does N4& respond by waking up, to voice or touch, or breathing normally another dose may be given. NARCAN Nasal Spray may be dosed every 2 to 3 minutes, if available. Repeat Step 2 using a new NARCAN Nasal Spray to give another dose in the other nostril. If additional NARCAN Nasal Sprays are available, repeat step 2 every 2 to 3 minutes until the person responds or emergency medical help is received. NOZZLE U G PLUNGER OHO CID �- HAND SUPPORTS HEAD KNEE STOPS BODY FROM ROLLING ONTO STOMACH For more information about NARCAN Nasal Spray, go to www.narcannasaispray.com, or call 1-844-4NARCAN (1-844-462-7226). ©2015 ADAPT Pharma, Inc. NARCAN° is a registered trademark licensed to ADAPT Pharma Operations Limited. A1009.01